Subclinical Hypothyroidism and Isolated Hypothyroxinemia during Pregnancy and Their Association with Pregnancy Outcome: A 2-Year Study

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Treatment of Subclinical Hypothyroidism or Hypothyroxinemia in Pregnancy.

BACKGROUND Subclinical thyroid disease during pregnancy may be associated with adverse outcomes, including a lower-than-normal IQ in offspring. It is unknown whether levothyroxine treatment of women who are identified as having subclinical hypothyroidism or hypothyroxinemia during pregnancy improves cognitive function in their children. METHODS We screened women with a singleton pregnancy bef...

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The Relationship between Gestational Diabetes and Subclinical Hypothyroidism in Pregnancy: A Narrative Study

Introduction: Thyroid disorders and gestational diabetes are the most common endocrine disorders during pregnancy. Given the important role of thyroid hormones in glucose metabolism and homeostasis, it seems that thyroid disorders can have significant effects on glucose metabolism and insulin secretion and may contribute to gestational diabetes. This review aimed to investigate the association ...

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Isolated maternal hypothyroxinemia during pregnancy: Knowns and unknowns

Isolated maternal hypothyroxinemia (IMH) during pregnancy is defined as a low maternal T4 in the absence of TSH elevation. As IMH is common, with a prevalence of 1-2% in iodine-sufficient populations, and early research has suggested adverse effects on fetal neurodevelopment, it has been the focus of many studies in the last decade. In the current review, we first discuss the significance of IM...

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Subclinical hypothyroidism: Identification and treatment in pregnancy

Thyroid disorders are the commonly detected endocrinopathies during pregnancy. It seems that prevalence of hypothyroidism is more in Asian countries compared with the West [1,2]. The majority of cases of hypothyroidism are considered to be subclinical type. In west, the prevalence of hypothyroidism is estimated to be 2-3% and 0.3-0.5% for subclinical and overt hypothyroidism respectively [2-4]....

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Hypothyroxinemia and pregnancy.

OBJECTIVE To evaluate the peer-reviewed literature on iodine deficiency and hypothyroxinemia in pregnancy. METHODS We review published studies on isolated hypothyroxinemia in pregnancy, methodology of free thyroxine (T4) assays, impact of iodine deficiency on free T4 levels, and status of ongoing prospective randomized trials of isolated hypothyroxinemia during pregnancy. RESULTS Hypothyrox...

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ژورنال

عنوان ژورنال: Open Journal of Obstetrics and Gynecology

سال: 2017

ISSN: 2160-8792,2160-8806

DOI: 10.4236/ojog.2017.77069